Heartland virus


  • New phlebovirus discovered in NW Missouri 2012, cases also describe in Tennessee[1]
  • Transmitted by lone star tick
  • 8 reported cases (as of 2014)[2]
Heartland virus cases
Year Location Deaths Cases
2009 Northwestern Missouri 0 2
2012-2013[3] Missouri, Tennessee[4] 1 6
2014 Missouri,[5] Oklahoma[6] 1 2

Clinical Features

  • Similar to other tick-born illnesses: fatigue, fever, arthralgias and myalgias
  • Diarrhea
  • Leukopenia, thrombocytopenia, elevated transaminases

Differential Diagnosis

Tick Borne Illnesses


  • No confirmatory testing available


  • Supportive measures


  • Discharge unless patient with other serious medical illness

See Also


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