• Infections spread by mosquitos, ticks, flies.
  • Dengue fever is the most common causes of arboviral disease around the world.
  • Increased incidence in warmer months.

Clinical Features

Differential Diagnosis


  • Detailed travel and exposure history
    • Local epidemiologic patterns helpful
  • Specific serologic testing


  • Symptomatic management
  • Exclude other causes if serious presentation
    • Consider empiric acyclovir and antibiotics until HSV and bacterial meningitis/encephalitis ruled out.


  • Takhar SS, Moran GJ. Disseminated Viral Infections. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD, T. eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York, NY: McGraw-Hill; 2011.
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