Clinical data
Synonyms BAY 86-5310; SH-T04211C
Routes of
By mouth[1]
Drug class Estrogen; Selective ERβ agonist
CAS Number

ZK-283197 (also known as BAY 86-5310 or SH-T04211C) is a selective and orally active ERβ agonist which was under development by Bayer Healthcare AG for the treatment of vasomotor symptoms.[1][2] It reached phase II clinical trials prior to the discontinuation of its development.[1] Its development was terminated in 2014.[1]


  1. 1 2 3 4 https://adisinsight.springer.com/drugs/800039952
  2. Pietras, R. J., & Jung, M. E. (2015). U.S. Patent Application No. 14/332,204. https://patents.google.com/patent/US20150018398A1

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.