VUF-6002

VUF-6002
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
Chemical and physical data
Formula C13H15ClN4O
Molar mass 278.737 g/mol
3D model (JSmol)
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VUF-6002 (JNJ-10191584) is a drug which acts as a potent and selective antagonist at the histamine H4 receptor.[1] It has antiinflammatory and analgesic effects in animal studies of acute inflammation.[2]

See also

References

  1. Zhang, M; Thurmond, RL; Dunford, PJ (2007). "The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders". Pharmacology & Therapeutics. 113 (3): 594–606. doi:10.1016/j.pharmthera.2006.11.008. PMID 17275092.
  2. Coruzzi, G; Adami, M; Guaita, E; De Esch, IJ; Leurs, R (2007). "Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation". European Journal of Pharmacology. 563 (1–3): 240–4. doi:10.1016/j.ejphar.2007.02.026. PMID 17382315.


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