P2RX5

P2RX5
Identifiers
AliasesP2RX5, LRH-1, P2X5, P2X5R, purinergic receptor P2X 5
External IDsMGI: 2137026 HomoloGene: 1924 GeneCards: P2RX5
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.2Start3,672,199 bp[1]
End3,696,404 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

5026

94045

Ensembl

ENSG00000083454

ENSMUSG00000005950

UniProt

Q93086

n/a

RefSeq (mRNA)

NM_175081
NM_001204519
NM_001204520
NM_002561
NM_175080

NM_033321

RefSeq (protein)

NP_001191448
NP_001191449
NP_002552
NP_778255

n/a

Location (UCSC)Chr 17: 3.67 – 3.7 MbChr 11: 73.16 – 73.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene.[5][6]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000083454 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005950 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Le KT, Paquet M, Nouel D, Babinski K, Seguela P (Jan 1998). "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system". FEBS Lett. 418 (1–2): 195–9. doi:10.1016/S0014-5793(97)01380-X. PMID 9414125.
  6. 1 2 "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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