Nitrofuran

Nitrofurans are a class of drugs typically used as antibiotics or antimicrobials.[1] The defining structural component is a furan ring with a nitro group.[2]

Members of this class of drugs include:

  • Antibacterials (antibiotics)
  • Antimicrobials
    • Furaltadone — an antiprotozoal
    • Furazidine — an antibacterial and antiprotozoal
    • Furylfuramide — a formerly used food preservative
    • Nifuratel — an antiprotozoal and antifungal
    • Nifurtimox — an antiprotozoal
  • FANFT, a potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.

References

  1. Chu, Pak-Sin; Lopez, Mayda I; Abraham, Ann; El Said, Kathleen R; Plakas, Steven M (2008). "Residue Depletion of Nitrofuran Drugs and Their Tissue-Bound Metabolites in Channel Catfish (Ictalurus punctatus) after Oral Dosing". Journal of Agricultural and Food Chemistry. 56 (17): 8030–8034. doi:10.1021/jf801398p. PMID 18698789.
  2. Vass, M; Hruska, K; Franek, M (2008). "Nitrofuran antibiotics: a review on the application, prohibition and residual analysis". Veterinární Medicína. 53: 469–500. doi:10.17221/1979-VETMED.
  3. Huttner, Angela; Verhaegh, Els M; Harbarth, Stephan; Muller, Anouk E; Theuretzbacher, Ursula; Mouton, Johan W (2015). "Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials". Journal of Antimicrobial Chemotherapy. 70 (9): 2456–2464. doi:10.1093/jac/dkv147. PMID 26066581.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.