Clinical data
ATC code
  • none
Legal status
Legal status
CAS Number
Chemical and physical data
Formula C27H33N3OS
Molar mass 447.64 g/mol
3D model (JSmol)

NESS-040C5 is a potent cannabinoid agonist which was developed for the treatment of glaucoma.[1] It has reasonable selectivity for the CB2 receptor subtype, having a CB2 affinity of 0.4nM, and 25x selectivity over the related CB1 receptor.[2]

See also


  1. Paolo Lazzari et al. Pharmaceutical Compounds. US Patent 8106218
  2. Hanus LO, Mechoulam R. Novel natural and synthetic ligands of the endocannabinoid system. Current Medicinal Chemistry. 2010;17(14):1341-59. PMID 20166928
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