Clinical data
Synonyms 9α,21-Dichloro-11β,17α-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 1-Dehydro-9α,21-dichloro-11β,17α-dihydroxy-16α-methylprogesterone
CAS Number
PubChem CID
Chemical and physical data
Formula C22H28Cl2O4
Molar mass 427.36 g·mol−1
3D model (JSmol)

Mometasone (INN, BAN), is a synthetic, steroidal glucocorticoid or corticosteroid that was never marketed.[1][2][3] The C17α furoate ester of mometasone, mometasone furoate, in contrast, has been marketed.[1][2][3] Mometasone furoate acts as a prodrug of mometasone.[4] In addition to its glucocorticoid activity, mometasone also has very potent progestogenic activity and acts as a partial agonist of the mineralocorticoid receptor.[5]


  1. 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 834–. ISBN 978-1-4757-2085-3.
  2. 1 2 Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 701–. ISBN 978-3-88763-075-1.
  3. 1 2 I.K. Morton; Judith M. Hall (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 185–. ISBN 978-0-7514-0499-9.
  4. Ruben Vardanyan; Victor Hruby (7 January 2016). Synthesis of Best-Seller Drugs. Elsevier Science. pp. 463–. ISBN 978-0-12-411524-8.
  5. Austin RJ, Maschera B, Walker A, Fairbairn L, Meldrum E, Farrow SN, et al. (2002). "Mometasone furoate is a less specific glucocorticoid than fluticasone propionate". Eur. Respir. J. 20 (6): 1386–92. doi:10.1183/09031936.02.02472001. PMID 12503693.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.