Hairmyres is an area of East Kilbride to the west side of the new town, sited on the main road to Eaglesham and Kilmarnock, and is located 2.2 miles from the Glasgow City Council boundary at the Carmunnock Bypass and 9 miles south from Glasgow City Centre. Hairmyres is where the district general hospital for the area is situated. The railway station (on the Glasgow Central to East Kilbride line) is at the bottom of the hospital drive. The trains are operated on a half-hourly basis by Abellio ScotRail Class 156 DMUs.
Next to Hairmyres Station is the UK government's Department for International Development, the joint headquarters of which is at 22 Whitehall, London. DFID (formerly ODA) relocated part of its operation to this site in c.1980 following a government initiative to create employment in a region (greater Glasgow) subject to major job losses following years of industrial decline.
The area is now has a small shopping area known as The St. James Retail Park. It is easily identifiable by its yellow and orange coloured walls. It hosts a few services such as eateries, a hairdresser and a vet.