GABRG1

GABRG1
Identifiers
AliasesGABRG1, gamma-aminobutyric acid type A receptor gamma1 subunit
External IDsMGI: 103156 HomoloGene: 22570 GeneCards: GABRG1
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4p12Start46,035,769 bp[1]
End46,124,081 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

2565

14405

Ensembl

ENSG00000163285

ENSMUSG00000001260

UniProt

Q8N1C3

Q9R0Y8

RefSeq (mRNA)

NM_173536

NM_010252

RefSeq (protein)

NP_775807

NP_034382

Location (UCSC)Chr 4: 46.04 – 46.12 MbChr 5: 70.75 – 70.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-aminobutyric acid receptor subunit gamma-1 is a protein that in humans is encoded by the GABRG1 gene.[5] The protein encoded by this gene is a subunit of the GABAA receptor.[6]

Variants of this gene may be associated with alcohol dependence.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000163285 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001260 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Wilcox AS, Warrington JA, Gardiner K, Berger R, Whiting P, Altherr MR, Wasmuth JJ, Patterson D, Sikela JM (July 1992). "Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5857–61. doi:10.1073/pnas.89.13.5857. PMC 49396. PMID 1321425.
  6. Hevers W, Lüddens H (August 1998). "The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes". Mol. Neurobiol. 18 (1): 35–86. doi:10.1007/BF02741459. PMID 9824848.
  7. Ittiwut C, Listman J, Mutirangura A, Malison R, Covault J, Kranzler HR, Sughondhabirom A, Thavichachart N, Gelernter J (January 2008). "Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4". Genomics. 91 (1): 61–9. doi:10.1016/j.ygeno.2007.08.007. PMC 2709929. PMID 17976953.

Further reading


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