Horton joined NFL Network at the start of the 2004 NFL season where he currently serves as an anchor, reporter and host. Horton provides in-depth interviews, post-game reports, and sideline reports for the Network. He also serves as the host and narrator for the Network's documentary series NFL Top 10.
Before working for NFL Network, Horton was a sportscaster for KCAL-TV in Los Angeles. This was before the CBS Corporation duopoly started and KCAL and KCBS consolidated their on-air and production teams.
Derrin was also on an episode of Spike TV's Pros VS. Joes, in which he lost in overtime to Sal Masekela. Derrin went to Syracuse University.
He is now Sports Director for KTLA to replace former sports director Damon Andrews.