|Chemical and physical data|
|Molar mass||284.376 g/mol|
|3D model (JSmol)|
Dacemazine (INN, also known as Ahistan and Histantine) is a phenothiazine derivative which acts as an histamine antagonist at the H1 subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl. It was also assessed as a possible anticancer drug.
- David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents. 1. Boca Raton: Chapman & Hall/CRC. p. 711. ISBN 0-412-46630-9. Retrieved on August 2, 2008 through Google Book Search.
- Karolyhazy G, Havas I, Jansco G, Kapas L, Sellei C. The anticarcinogenic effect of dimethylaminoacetyl-phentiazide (ahistan). Kiserletes Orvostudomany. 1952 Aug;4(4):260-2. PMID 13023855
See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors
(TCAs and TeCAs)