DNQX

DNQX
Names
IUPAC name
6,7-Dinitroquinoxaline-2,3(1H,4H)-dione
Identifiers
3D model (JSmol)
ChEMBL
DrugBank
Properties
C8H4N4O6
Molar mass 252.14 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

DNQX (6,7-dinitroquinoxaline-2,3-dione) is a competitive antagonist at AMPA and kainate receptors, two ionotropic glutamate receptor (iGluR) subfamilies.[1] It is used in a variety of molecular biology subfields, notably neurophysiology, to assist researchers in determining the properties of various types of ion channels and their potential applications in medicine.

See also

References

  1. Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R (September 2010). "Glutamate receptor ion channels: structure, regulation, and function". Pharmacological Reviews. 62 (3): 405–96. doi:10.1124/pr.109.002451. PMC 2964903. PMID 20716669.
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