Clinical data
Trade names Cyclomate, Estrumate
Routes of
ATCvet code
Pharmacokinetic data
Excretion 67% renal, 25% fecal
CAS Number
PubChem CID
Chemical and physical data
Formula C22H29ClO6
Molar mass 424.915
3D model (JSmol)

Cloprostenol is a synthetic analogue of prostoglandin F (PGF).[1] It is a potent luteolytic agent; this means that, within hours of administration, it causes the corpus luteum to stop production of progesterone, and to reduce in size over several days.[1] This effect is used in animals to induce estrus and to cause abortion.[2]


  1. 1 2 Cooper, M. (1 January 1981). "Prostaglandins in veterinary practice". In Practice. 3 (1): 30–34. doi:10.1136/inpract.3.1.30.
  2. Plumb, DC (2015). "Cloprostenol Sodium". Plumb's Veterinary Drug Handbook (8th ed.). Wiley. ISBN 9781118911938.

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