Combination of
Androstendione Androstane steroid
Human serum albumin Serum protein
Clinical data
Trade names Androvax
Synonyms Androstenedione:human serum albumin conjugate
AHFS/ Monograph
  • US: X (Contraindicated)
    Legal status
    Legal status
    • None

    Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes.[1][2][3] It is a conjugate of androstenedione and human serum albumin.[1][3] The drug is marketed in New Zealand.[1][3]

    Androvax produces immunity against androstenedione, and the generation of antibodies against androstenedione decreases circulating levels of androstenedione.[1] In addition, since androstenedione is the major precursor of estrogens, estrogen levels are decreased as well.[1] This is thought to result in reduced negative feedback on the hypothalamic-pituitary-gonadal axis and increased gonadotropin secretion, which in turn improves fertility and fecundity.[1]

    See also


    1. 1 2 3 4 5 6 Satish Kumar Jindal; M. C. Sharma (2010). Biotechnology in Animal Health and Production. New India Publishing. pp. 77–. ISBN 978-93-80235-35-6.
    2. Reproductive Technologies in Farm Animals. CABI. 2004. pp. 206–. ISBN 978-0-85199-049-1.
    3. 1 2 3

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