To me, it sounds no different at all but I'm not sure of it. Do they have the same meaning?
You have nothing to do with it. OR It has nothing to do with you.
4am has nothing to do with your English level. OR Your English level has nothing to do with 4am.
For second example, I told one of my friend who read the reading practice at 4am as she was awoken and said "Tired 4am voice". I always adore her accent and pronunciation.
I have no idea how to provide my research for this kinda question. Thanks.